Fa'idodin Cire Saffron: Magani na Halitta don Rage nauyi da Kyakkyawan yanayi

1. Game da tsantsar Saffron

An fitar da samfurin daga babban sashi na salon da kuma rashin kunya na Crocus sativus L., shuka iris. Babban sinadaran sun hada da picrocrocin, carotene mahadi, safflower aldehyde, eucalyptol, pinene da sauran abubuwa, da kuma dauke da wani karamin adadin Isorhamnetin, kaempferol, bitamin B1 da bitamin B2, da dai sauransu Saffron tsantsa ne mai iko scavenger na hydroxyl free radicals da superoxide. masu tsattsauran ra'ayi. Yana iya tsayayya da halayen iskar shaka, inganta aikin mitochondrial, hana apoptosis cell jijiyar gani, inganta microcirculation, inganta rigakafi, tsayayya da arteriosclerosis, da tsayayya da iskar shaka. Yana da ayyuka na rage yawan lipids na jini, inganta cututtukan choleretic da kariyar hanta, rigakafi da magance osteoporosis, da kare koda.

Tushen shuka

 

2. Asalin shuka

Asalin asali] Shi ne babban ɓangare na salo da rashin kunya na shuka iris Crocus sativus L.

【Alias】 Crocus, saffron.

[Rarrabawa] Akwai ƙaramin adadin noman gwaji a Beijing, Shanghai, Shandong, Zhejiang, Sichuan, Xinjiang, da sauransu a China, kuma ana noma shi a ƙasashen waje a Spain, Iran, Italiya, Jamus, Faransa, Girka, Austria, tsohuwar Tarayyar Soviet da Japan.

【Siffofin Shuke-shuke】Ganye masu tsawon rai. Kwalaben ƙarƙashin ƙasa suna da siffar zagaye kuma an rufe su da ganyen launin ruwan kasa mai siffar manne. Akwai ganyaye 9 zuwa 15, waɗanda aka girma daga kwan fitila, sessile, kunkuntar da layi, tsawon 15 zuwa 20 cm da faɗin 2 zuwa 3 cm. Gefen ganyen suna da laushi kuma suna da gashi mai kyau, kuma tushen yana kewaye da sikelin 4 zuwa 5. . Furanni masu faɗi, diamita 2.5-3 cm; perianth mai yanki 6, obovate, lavender, bututun fure mai tsawon 4-6 cm, siririn siffar bututu, stamens 3, manyan anthers, tushe mai siffar kibiya, pistils 3, connate carpels, kwai yana ƙasa, salon siriri ne, rawaya, saman yana da lobes uku masu zurfi, suna fitowa daga bututun fure, suna faɗuwa, ja mai duhu, saman stigma yana ɗan faɗaɗa, tare da buɗewa a cikin siffar mazurari. Kwandon yana da tsayi, yana da gefuna uku masu kaifi, kimanin tsawon cm 3 da faɗin cm 1.5. Yana isa ƙasa lokacin da 'ya'yan itacen suka girma. Iri suna da yawa, suna da siffar zagaye, kuma gashin iri yana da laushi. Lokacin fure daga farkon zuwa tsakiyar Nuwamba

3. Sinadaran sinadarai

1). Man Fetur Mai Sauyawa Man Fetur mai canzawa a cikin pistil (ƙazanta) na saffron corolla ana samar da shi ne ta hanyar lalacewar carotenes kamar zeaxanthin kuma yana da tsari na musamman. Ya fi safranal a cikin abubuwan da aka samo daga trimethylcycloethylene, wanda ya kai kashi 50% na jimlar man fetir. Kashi 72%, shine samfurin lalata crocin, kuma yana ɗaya daga cikin alamun kula da inganci na maganin gargajiya na kasar Sin Zangsafflower. Wasu masana sun gano mahadi 46 daga man fetir mai sauro, wanda ya kai kashi 90.99% na jimlar man fetir. Daga cikinsu, mahaɗan ketone guda 5 sun kai kashi 6.16%, mahaɗan aldehyde guda 5 sun kai kashi 2.39%, mahaɗan barasa guda 6 sun kai kashi 4.98%, mahaɗan acid guda 6 sun kai kashi 19.77%, mahaɗan olefin guda 8 sun kai kashi 36.42%, kuma mahaɗan olefin oxides guda 2 sun kai kashi 5.74%, mahaɗan alkane guda 8 sun kai kashi 12.5%, mahaɗan ester guda 2 sun kai kashi 0.48%, da kuma wasu mahaɗan 4 sun kai kashi 2.55%. Daga cikin abubuwan da aka gano na man fetur masu canzawa na saffron, waɗanda ke da babban abun ciki galibi sune olefins da olefin oxides, waɗanda mahaɗan terpenoid ne. Bugu da ƙari, waɗanda ke da babban abun ciki sune mahaɗan acid.

2). Flavonoids Flavonoids galibi suna yaɗuwa ne a cikin perianth na saffron. Wadanda aka fi sani sun haɗa da vetch glycoside, quercetin-3-p-coumaroylglucoside, kaempferol-3-glucose-6-acetylglucoside da Kaempferol-3-glucose-glucoside, delphinidin, trimethyldelphinidin, da sauransu.

3). Abubuwan da ke haifar da mai mai canzawa. Wani ɓangare na abubuwan da ke haifar da mai mai canzawa da ake samarwa ta hanyoyi daban-daban na lalacewa yayin bushewa da adana saffron sune mahaɗan glycoside na abubuwan da ke haifar da trimethylcyclohexene, galibi sun haɗa da crocin da sauransu. Crocein shine babban sinadarin da ke cikin saffron. Ana iya canza shi zuwa safranal a ƙarƙashin yanayin acidic ko alkaline ko ƙarƙashin aikin enzymes. Wannan kuma shine dalilin da ya sa abubuwan da ke cikin safranal a cikin nau'ikan daban-daban suka bambanta.

4). Polyenes masu haɗin gwiwa da glycosides ɗinsu Polyenes masu haɗin gwiwa da glycosides ɗinsu sune manyan abubuwan da ke cikin maganin gargajiya na kasar Sin na saffron. Ya ƙunshi waɗannan rukunoni guda biyu: (1) Carotenoids da glycosides ɗinsu. Crocetin shine babban sinadarin carotenoids da glycosides ɗinsu. Ya haɗa da carotenoid crocetin da glycosides ɗinsa, kamar gentiobioside, glucoside, digentisic acid glycoside, gentioglucoside da diglucoside; B-crocetin, C-crocetin, da sauransu. (2) Carotenes galibi sun haɗa da A da B-carotene, kamar lycopene da zeaxanthin.

5). Sauran sun hada da phenols, chitinase, triterpene saponins da saponins na steroidal.

4. Ayyukan harmacological P

1). Tasirin da ke kan mahaifa. Cirewar Saffron yana da tasiri mai ban sha'awa ga mahaifar da aka keɓe da kuma mahaifar da ke cikin jiki ta beraye, aladu na Guinea, zomaye, karnuka da kuliyoyi. Mahaifa mai ciki ta fi saurin kamuwa; tsarin yawan ruwan safranin daban-daban shine: decoction > ethanol extract > activities activities > ether extract. Tasirin tashin hankalin mahaifa na iya toshewa kaɗan ta hanyar ergotamine ethanesulfonate, wanda ba shi da saurin kamuwa da atropine. Saboda haka, ana kyautata zaton cewa wani ɓangare na tasirin da ke kan mahaifa yana da tasiri kai tsaye ga ƙwayoyin cuta na mahaifa, kuma wani ɓangare yana da alaƙa da masu karɓar adrenergic.

2). Tasiri ga tsarin zagayawar jini. Ruwan Saffron zai iya rage hawan jini na karnuka da kuliyoyi da aka yi wa sa barci na dogon lokaci kuma yana da tasiri mai ban sha'awa akan numfashi. Lokacin rage hawan jini, ƙarar koda tana raguwa, wanda ke nuna toshewar koda, kuma yana da tasiri mai ƙarfi akan jijiyoyin jinin kwai. Yana da tasiri mai mahimmanci akan zuciyar kwai da aka keɓe. A cewar binciken sinadarai, abubuwan da ke hana zuciya suna da alaƙa da gishirin potassium. Saboda haka, binciken magunguna na gaba akan saffron ya kamata ya fara cire gishirin potassium.

3). Tasirin hana ƙari. Shirye-shiryen Saffron suna da ikon hana ƙari da hana ciwon daji, musamman ruwan saffron (dimethylcrocetin) akan cutar sankarar bargo, ciwon daji na ovarian, ciwon daji na hanji, rhabdomyosarcoma, ciwon daji na hanji, papillosarcoma, da ciwon ƙwayoyin halitta mai faɗi da sarcoma nama mai laushi, da sauransu. Duk suna da tasirin hana kumburi. Tsarin hana ciwon daji na iya zama lalata tsarin DNA synthase, wato, lalata masu shiga tsakani na hulɗa da furotin na DNA kamar topoisomerase II waɗanda ke da mahimmanci ga haɗakar DNA ta salula, ta haka yana hana haɗakar DNA da RNA, ta haka yana hana haɓakar ƙwayoyin ƙari. sakamako. Bugu da ƙari, crocins kuma suna hana aikin kinases na furotin tantanin halitta da bayyanar proto-oncogenes.

4). Tasiri ga hanta da gallbladder. Ruwan Saffron yana da tasirin choleretic, kuma sinadaran da ke cikinsa sune gishirin sodium na α-crocetin da crocetin ester. α-Saffron acid na iya rage cholesterol da kuma ƙara yawan kitse. Ana iya amfani da shi tare da magungunan gargajiya na kasar Sin kamar hawthorn, cassia, da Alisma don magance kitsen hanta.

5) Tasirin antioxidant. Cirewar Saffron, musamman crocin, na iya hana ayyukan radicals masu ɗauke da iskar oxygen da xanthine oxidase yadda ya kamata, wanda ke nuna aikin ƙwayoyin halitta na antioxidant.

6). Kare kodan. Ta hanyar nazarin samfurin beraye na C-BSA nephritis, an gano cewa an rage yawan lalacewar proteinuria da lalacewar koda a cikin beraye a cikin rukunin gwaji. Daga cikinsu, saffron galibi yana hana cyclooxygenase kuma yana rage haɗakar prostaglandins, ta haka yana buɗe ƙwayoyin koda, yana ƙara kwararar jini, da kuma haɓaka gyaran lalacewar kumburi. Ana ba da shawarar cewa saffron na iya tsoma baki ga faruwar kumburin koda ta hanyar inganta sakin platelets da masu shiga tsakani na kumburi.

7) Shisshigi a cikin arrhythmia Crocemic acid, sinadari mai aiki a cikin ruwan saffron, yana da kyakkyawan tasiri akan samfuran arrhythmia na ventricular wanda aconitine, ouabain da calcium chloride suka haifar, yana ba da gwaje-gwaje don amfani da saffron wajen magance arrhythmia. Wannan yana ba da tushen yuwuwar ci gaba da bincike kan saffron a matsayin wani shiri na maganin gargajiya na kasar Sin don magance arrhythmia da ischemia na zuciya, yana nuna cewa ana iya kiran saffron sabon nau'in maganin gargajiya na kasar Sin na rigakafi don hana cututtukan zuciya da jijiyoyin jini.

8). Daidaita aikin garkuwar jiki. Ruwan Saffron yana da tasiri a bayyane na inganta zagayawar jini da kuma kawar da tsatsa a jini, maganin kashe ƙwayoyin cuta da kuma hana kumburi, sannan kuma yana ƙara juriyar jiki da kuma ƙara yawan ƙwayoyin garkuwar jiki, ta haka yana inganta garkuwar jiki, yana daidaita motsin qi da jini a jiki, da kuma daidaita jikin ɗan adam. Matsayin yin da yang.

9). Hana da kuma magance atherosclerosis. Ruwan Saffron yana da tasiri mai kyau wajen daidaita sinadarin lipids a cikin jini, rage hawan jini, don haka yana hana da kuma magance atherosclerosis.

10). Kariyar Retina: An yi amfani da zomaye fararen fata na New Zealand don ƙirƙirar samfurin dabba na matsin lamba mai yawa a ido. An yi allurar wani nau'in maganin saffron daga jijiyar kunne sau ɗaya a rana, kuma an kafa ƙungiyar kula da matsin lamba mai yawa. Sakamakon ya nuna cewa adadin ƙwayoyin ganglion na retinal a cikin rukunin jiyya ya fi na ƙungiyar kula da matsin lamba mai yawa (P<0.05), yana nuna cewa maganin saffron ya inganta zagayawar jini na retina kuma ya toshe tasirin ischemia da hypoxia akan ƙwayoyin ganglion na retina a ƙarƙashin lalacewar yanayin matsin lamba mai yawa a ido (RGC) da kuma kare RGC. Ana ba da shawarar cewa maganin saffron na iya kare RGCs ta hanyar rage ƙwayoyin cuta masu kyauta a cikin retina da kuma toshe lalacewar ƙwayoyin cuta masu kyauta ga tsarin membrane, ƙwayoyin halitta da ƙwayoyin halitta na RGCs. 11. Sauran tasirin: Cirewar ethanol na Saffron (CSE) na iya hana hana dogon lokaci na ethanol (LPT) a cikin hippocampus. A cikin serrated gyrus na beraye da aka yi wa sa barci, CSE (250 mg·kg-1) kuma zai iya hana LPT da acetaldehyde ke haifarwa ba tare da shafar aikin koyon beraye ba. Ruwan da aka fitar daga saffron zai iya hana gubar haihuwa da magungunan hana ciwon daji ke samarwa kamar cisplatin, cyclophosphamide, mitomycin C da urethan, yayin da yake hana. Girman tasirin bai shafi yawan amfani ba. Wannan ya faru ne saboda sinadarin saffron yana rage tasirin gubar haihuwa akan hanta glutathione S-transferase (GST). Yanayi, dandano da inganci: mai daɗi, tsaka tsaki kuma mara guba. Yana shiga cikin zuciya da hanta. Yana haɓaka zagayawar jini kuma yana kawar da stasis na jini, yana wargaza damuwa da buɗe kulli. Ana iya amfani da shi don magance baƙin ciki, matsewar ƙirji da diaphragm, amai da jini, zazzabin typhoid, tsoro da jin zafi, amenorrhea a cikin mata, tashin jinin bayan haihuwa da ciwon ciki, da kumburi da zafi daga faɗuwa.

              

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